After 12 years, The Last of Us director has settled the discussion about the ending, but fans aren't satisfied
Naughty Dog CEO and The Last of Us co-creator Neil Druckmann has ended the long-standing debate over the chance to make a cure, which was dashed by Joel in the first installment of the series.

WARNING! The following article reveals plot details of The Last of Us!
The finale of the first installment of The Last of Us is not only one of the most memorable moments of the series, but also the most frequently discussed. Many debates among fans have been sparked by the fact that they never received an answer to the question: Did the Fireflies ever have a chance to create a cure that would save humanity by sacrificing Ellie's life?
Meanwhile, 12 years after the release of the first part, Neil Druckmann ended this long-standing discussion. During a recent interview for Sacred Symbols (via GamesRadar), the developer clearly confirmed that in the game's universe, there was a real possibility of creating a cure for the cordyceps infection.
All I can say is that our intent is that they would have made a cure - revealed Druckmann, adding: That makes the most interesting philosophical question for what Joel does.
Will such knowledge reassure the fans? Looking at the comments under the clip published on Reddit - not entirely. s seem to be dissatisfied with the fact that Druckmann dispelled all doubts about the ending. According to some of them, it was better to leave this issue open.
Moreover, they believed that the game intentionally portrayed the healing process as very uncertain. The head doctor of the Fireflies was actually a vet working in a run-down hospital, with no real resources to make medicine.
It's hard to resist the impression that, not knowing the answer, the players could somehow justify Joel's decision, who, at the cost of Ellie's life, doomed humanity to extinction.