Oblivion: Next of Kin

Talk to Perennia Draconis - she'll take you for a gift deliverer of some sort and provide you with a list of her children. Kill her and start your Draconis-killing marathon throughout Cyrodiil.

Matthias Draconis works in Umbacano Manor In Talos Plaza. You can ambush him any time of the day - just don't do it on the streets or the guards will be all over you.

Caelia Draconis is a city guard in Leyawiin. Each day around noon she's spending some time alone in a room in Three Sisters. If you can't sneak-kill her, she'll probably give you a standard city guard speech - you'll have to choose "resist arrest" option and finish her off.

Andreas Draconis is an innkeeper of the Drunken Dragon Inn in the eastern parts of Cyrodiil. His inn is always guarded by a fully armed guard, but you should manage to deal with the problem quietly (preferably during the night hours).

Sybilla Draconis is in Muck Valley Cavern, inhabited also by bears and wolves. It's quite simple here - go through the cave and do your thing.